Journal of the American Dental Association, Vol 99, Issue 4, 652-655
Copyright © 1979 by American Dental Association
Summary of an International Symposium on phenytoin-induced teratology and gingival pathology
TM Hassell,
KH Dudley,
PF Hirsch,
LH Hutchens,
MC Johnston,
and
JD Moriarty
Phenytoin has been the preferred drug for treating grand mal epilepsy for more than 40 years. The metabolism of this drug, its teratogenic potential, and its role in the pathogenesis of gingival overgrowth are discussed.