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J Am Dent Assoc, Vol 139, No suppl_5, 19S-24S.
© 2008 American Dental Association

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ARTICLES

JADA Continuing Education

The Relationship Between Oral Health and Diabetes Mellitus



Ira B. Lamster, DDS, MMSc, Evanthia Lalla, DDS, MS, Wenche S. Borgnakke, DDS, PhD and George W. Taylor, DMD, DrPH

Background. The term "diabetes mellitus" describes a group of disorders characterized by elevated levels of glucose in the blood and abnormalities of carbohydrate, fat and protein metabolism. A number of oral diseases and disorders have been associated with diabetes mellitus, and periodontitis has been identified as a possible risk factor for poor metabolic control in subjects with diabetes.

Methods. The authors reviewed the literature to identify oral conditions that are affected by diabetes mellitus. They also examined the literature concerning periodontitis as a modifier of glycemic control.

Results. Although a number of oral disorders have been associated with diabetes mellitus, the data support the fact that periodontitis is a complication of diabetes. Patients with long-standing, poorly controlled diabetes are at risk of developing oral candidiasis, and the evidence indicates that periodontitis is a risk factor for poor glycemic control and the development of other clinical complications of diabetes. Evidence suggests that periodontal changes are the first clinical manifestation of diabetes.

Conclusions. Diabetes is an important health care problem. The evidence suggests that oral health care providers can have a significant, positive effect on the oral and general health of patients with diabetes mellitus.

Key Words: Diabetes mellitus; oral health; oral candidiasis; periodontitis

Abbreviations: AGE: Advanced glycation endproduct. • GPD: General practice dentist. • HbA1c: Glycosylated hemoglobin. • NHANES III: Third National Health and Nutrition Examination Survey. • RAGE: Receptor for AGE.







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