HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

J Am Dent Assoc, Vol 138, No 1, 80-85. © 2007 American Dental Association

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Brennan, M. T. Articles by Lockhart, P. B. Search for Related Content PubMed PubMed Citation Articles by Brennan, M. T. Articles by Lockhart, P. B. Related Collections Infection Control

JADA Continuing Education

Background. The authors examine the role of dental disease and nonsurgical dental procedures in the incidence and duration of bacteremia in children.

Methods. The authors randomized a group of children to receive amoxicillin or a placebo before dental rehabilitation in an operating room setting. They collected eight blood draws at the following times: two minutes after intubation (draw 1); after dental restorations, pulp therapy and cleaning (draw 2); 10 minutes later (draw 3); and five draws during and after dental extractions (draws 4–8). The authors compared dental disease parameters and the type of dental procedures performed with the incidence and duration of bacteremia.

Results. The authors enrolled 100 children (aged 1–8 years) in the study. The incidence of bacteremia from draw 2 was 20 percent in the placebo group and 6 percent in the amoxicillin group (P = .07), and the incidence from draw 3 was 16 percent in the placebo group and zero percent in the amoxicillin group (P = .03). Subjects with higher gingival scores were more likely to have a bacteremia for draw 2 (P = .01). The authors found that subjects in the group with bacteremia for draw 3 had undergone more pulpotomies than did subjects in the group without bacteremia for draw 3 (3 ± 2.5 standard deviation [SD] versus 1.5 ± 1.6 SD, P = .04), while they found almost no differences for draw 2.

Conclusions. This study suggests that gingival disease has an impact on bacteremia after dental restorations and prophylaxis. Although antibiotics have an impact, they do not eliminate bacteremia altogether.

Key Words: Bacteremia; infective endocarditis; pediatric dental care; gingival diseases

Abbreviations: AHA: American Hospital Association • IE: Infective endocarditis • IND: Incidence, nature (species of bacteria) and duration • OR: Operating room

This article has been cited by other articles:

				N. B. Parahitiyawa, L. J. Jin, W. K. Leung, W. C. Yam, and L. P. Samaranayake Microbiology of Odontogenic Bacteremia: beyond Endocarditis Clin. Microbiol. Rev., January 1, 2009; 22(1): 46 - 64. [Abstract] [Full Text] [PDF]

				I. Uckay, D. Pittet, L. Bernard, D. Lew, A. Perrier, and R. Peter Antibiotic prophylaxis before invasive dental procedures in patients with arthroplasties of the hip and knee J Bone Joint Surg Br, July 1, 2008; 90-B(7): 833 - 838. [Abstract] [Full Text] [PDF]