Journal of the American Dental Association, Vol 114, Issue 6, 814-816
Copyright © 1987 by American Dental Association
New developments in understanding phenytoin-induced gingival hyperplasia
E Stinnett,
B Rodu,
and
WE Grizzle
In approximately half of the patients taking phenytoin, gingival fibroblasts proliferate, causing tissue overgrowth and gingival hyperplasia. Recent clinical and basic research is reviewed, describing the conditions associated with phenytoin therapy and gingival hyperplasia.